Player | GP | CMP | ATT | YDS | TD | INT | |
|---|---|---|---|---|---|---|---|
  | Joe Burrow CIN Bengals | 17 | 460 | 652 | 4918 | 43 | 9 |
  | Lamar Jackson BAL Ravens | 17 | 316 | 474 | 4172 | 41 | 4 |
  | Baker Mayfield TB Buccaneers | 17 | 407 | 570 | 4500 | 41 | 16 |
  | Jared Goff DET Lions | 17 | 390 | 539 | 4629 | 37 | 12 |
  | Sam Darnold MIN Vikings | 17 | 361 | 545 | 4319 | 35 | 12 |
  | Bo Nix DEN Broncos | 17 | 376 | 567 | 3775 | 29 | 12 |
  | Josh Allen BUF Bills | 17 | 307 | 483 | 3731 | 28 | 6 |
  | Aaron Rodgers NYJ Jets | 17 | 368 | 584 | 3897 | 28 | 11 |
  | Patrick Mahomes KC Chiefs | 16 | 392 | 581 | 3928 | 26 | 11 |
  | Jayden Daniels WAS Commanders | 17 | 331 | 480 | 3568 | 25 | 9 |
  | Jordan Love GB Packers | 15 | 268 | 425 | 3389 | 25 | 11 |
  | Justin Herbert LAC Chargers | 17 | 332 | 504 | 3870 | 23 | 3 |
  | Geno Smith SEA Seahawks | 17 | 407 | 578 | 4320 | 21 | 15 |
  | Kyler Murray ARI Cardinals | 17 | 372 | 541 | 3851 | 21 | 11 |
  | Caleb Williams CHI Bears | 17 | 351 | 562 | 3541 | 20 | 6 |
  | Matthew Stafford LAR Rams | 16 | 340 | 517 | 3762 | 20 | 8 |
  | Brock Purdy SF 49ers | 15 | 300 | 455 | 3864 | 20 | 12 |
  | C.J. Stroud HOU Texans | 17 | 336 | 532 | 3727 | 20 | 12 |
  | Tua Tagovailoa MIA Dolphins | 11 | 291 | 399 | 2867 | 19 | 7 |
  | Kirk Cousins ATL Falcons | 14 | 303 | 453 | 3508 | 18 | 16 |
  | Jalen Hurts PHI Eagles | 15 | 248 | 361 | 2903 | 18 | 5 |
  | Russell Wilson PIT Steelers | 11 | 214 | 336 | 2482 | 16 | 5 |
  | Drake Maye NE Patriots | 13 | 225 | 338 | 2276 | 15 | 10 |
  | Derek Carr NO Saints | 10 | 189 | 279 | 2145 | 15 | 5 |
  | Bryce Young CAR Panthers | 14 | 234 | 384 | 2403 | 15 | 9 |
  | Jameis Winston CLE Browns | 12 | 181 | 296 | 2121 | 13 | 12 |
  | Will Levis TEN Titans | 12 | 190 | 301 | 2091 | 13 | 12 |
  | Joe Flacco IND Colts | 8 | 162 | 248 | 1761 | 12 | 7 |
  | Cooper Rush DAL Cowboys | 12 | 187 | 308 | 1844 | 12 | 5 |
 | Dak Prescott DAL Cowboys | 8 | 185 | 286 | 1978 | 11 | 8 |
  | Trevor Lawrence JAX Jaguars | 10 | 172 | 284 | 2045 | 11 | 7 |
 | Mason Rudolph TEN Titans | 8 | 146 | 228 | 1530 | 9 | 9 |
  | Gardner Minshew LV Raiders | 10 | 203 | 306 | 2013 | 9 | 10 |
 | Aidan O'Connell LV Raiders | 9 | 154 | 243 | 1612 | 8 | 4 |
 | Daniel Jones MIN Vikings | 10 | 216 | 341 | 2070 | 8 | 7 |
 | Mac Jones JAX Jaguars | 10 | 171 | 262 | 1672 | 8 | 8 |
 | Anthony Richardson IND Colts | 11 | 126 | 264 | 1814 | 8 | 12 |
 | Andy Dalton CAR Panthers | 6 | 106 | 160 | 989 | 7 | 6 |
  | Drew Lock NYG Giants | 8 | 107 | 181 | 1071 | 6 | 5 |
 | Deshaun Watson CLE Browns | 7 | 137 | 216 | 1148 | 5 | 3 |
 | Justin Fields PIT Steelers | 10 | 106 | 161 | 1106 | 5 | 1 |
 | Spencer Rattler NO Saints | 7 | 130 | 228 | 1317 | 4 | 5 |
 | Marcus Mariota WAS Commanders | 3 | 34 | 44 | 364 | 4 | 0 |
 | Tanner McKee PHI Eagles | 2 | 30 | 45 | 323 | 4 | 0 |
 | Michael Penix ATL Falcons | 5 | 61 | 105 | 775 | 3 | 3 |
 | Tyler Huntley MIA Dolphins | 5 | 86 | 133 | 829 | 3 | 3 |
 | Malik Willis GB Packers | 7 | 40 | 54 | 550 | 3 | 0 |
 | Tyrod Taylor NYJ Jets | 2 | 17 | 22 | 119 | 3 | 0 |
 | Jimmy Garoppolo LAR Rams | 1 | 27 | 41 | 334 | 2 | 1 |
 | Jacoby Brissett NE Patriots | 8 | 95 | 161 | 826 | 2 | 1 |
 | Mitchell Trubisky BUF Bills | 9 | 19 | 26 | 179 | 2 | 0 |
 | Joshua Dobbs SF 49ers | 2 | 32 | 47 | 361 | 2 | 2 |
 | Desmond Ridder LV Raiders | 6 | 52 | 85 | 458 | 2 | 2 |
 | Kenny Pickett PHI Eagles | 5 | 25 | 42 | 291 | 2 | 1 |
 | Jake Haener NO Saints | 8 | 18 | 39 | 226 | 1 | 1 |
 | Joe Milton NE Patriots | 1 | 22 | 29 | 241 | 1 | 0 |
 | Brandon Allen SF 49ers | 3 | 17 | 30 | 199 | 1 | 2 |
 | Tim Boyle NYG Giants | 3 | 27 | 50 | 276 | 1 | 1 |
 | Bailey Zappe CLE Browns | 1 | 16 | 31 | 170 | 1 | 2 |