Christian McCaffrey (Achilles) is targeting an early November return, per @RapSheet

Browns RB Nick Chubb (knee) has been ruled out for Week 6.

Colts RB Jonathan Taylor has been ruled OUT for Sunday's game against the Titans. QB Anthony Richardson is a game-time decision.

Steelers QB Russell Wilson will be active on Sunday and serve as the No. 2 behind Justin Fields, per HC Mike Tomlin.

Bengals RBs Zack Moss and Chase Brown are “good to go” for Sunday’s game against the Giants, per HC Zac Taylor.

49ers RB Jordan Mason, is believed to have suffered a sprained AC joint on TNF that is not considered to be serious, per @AdamSchefter He will undergo further testing.

Giants WR Malik Nabers (concussion) is OUT again this Sunday vs. Bengals, per Brian Daboll.

Seahawks WR Tyler Lockett is headed to the locker room.

Jordan Mason has jogged out of the locker room and rejoined his teammates on the sideline (with his helmet on).