49ers RB Christian McCaffrey is targeting an early November return as he rehabs from Achilles tendinitis, per @RapSheet

Jaguars RB Travis Etienne (shoulder) is questionable to return

Joe Flacco is in the game at QB for the Colts for an injured Anthony Richardson

Rams WR Cooper Kupp (ankle) will miss at least the next 2 weeks, and Puka Nacua (knee) is out at least another month, per @JayGlazer

Steelers QB Russell Wilson is inactive for the 4th week in a row, per @AdamSchefter Will Russ ever start for the Steelers?

Keenan Allen (heel) is active today

Chris Olave and Alvin Kamara will both be active for the Saints today, per @nick_underhill

Texans RB Joe Mixon will be OUT today vs the Jaguars due to his ankle injury, per @Schultz_Report

Buccaneers RBs Rachaad White and Bucky Irving, both listened as questionable, are expected to play today, per @AdamSchefter