Chiefs RB Isiah Pacheco has a fractured fibula, per @RapSheet

Alec Pierce (IND-WR) now has 18.1 fantasy points in PPR (14.1 standard), outperforming his projection by 10.57 points with 00:02 remaining in the 4 quarter

Vikings RB Aaron Jones is headed to the medical tent.

Marquez Valdes-Scantling (NO-WR) now has 18.6 fantasy points in PPR (16.6 standard), outperforming his projection by 12.64 points with 5:45 remaining in the 2 quarter

Jaguars RB Tank Bigsby is questionable to return with an ankle injury.

Giants WR Malik Nabers is being evaluated for a concussion.

Bills WR Amari Cooper is OUT today against the Colts, per @RapSheet

The cart is out for Panthers RB Miles Sanders.

49ers RB Christian McCaffrey is expected to get approx 20 touches today, per @MikeGarafolo A normal-ish workload for CMC.