BREAKING - The Jaguars & QB Trevor Lawrence have agreed on a 5-year $275M contract extension, per @RapSheet The deal comes with $200M guaranteed.

49ers TE George Kittle (hamstring) is questionable for Sunday’s game against Seattle, per @AdamSchefter

The Jaguars have ruled out QB Trevor Lawrence and RB Tank Bigsby for Sunday's game at Detroit, per @TomPelissero

Seahawks WR D.K. Metcalf is off the injury report and good to go for Sunday’s game against San Francisco, per @AdamSchefter

The Lions have ruled out TE Sam LaPorta (shoulder) for this week’s game vs the Jaguars, per @RapSheet

Texans WR Nico Collins (hamstring) is "100% ready to go" for Monday.

Falcons WR Darnell Mooney (Achilles) no longer has an injury designation and will play Sunday, per @marcraimondi

RB MarShawn Lloyd woke up this morning with appendicitis, per Packers HC Matt LaFleur. A unique situation since Lloyd’s 21-day practice window is already open… The Packers are talking to the NFL to see if there’s a way he can still play later this season.

Colts WR Michael Pittman Jr. (back) plans to play Week 11.